Kevin Youkilis had a career-high six RBIs, thanks to his first grand slam, and Tim Wakefield pitched seven innings of two-hit ball Saturday night to lead the Boston Red Sox to a 12-1 victory over the Baltimore Orioles.

J.D. Drew and Manny Ramirez homered on consecutive pitches in the first inning, and Youkilis cleared the bases in the third when the Red Sox scored seven times to chase Radhames Liz (3-2). Youkilis also added a sacrifice fly in the fourth and a run-scoring infield single in the eighth.